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Surgeons successfully transplanted genetically engineered pig’s heart into human patient

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The University of Maryland School of Medicine announced on Monday January 10 that the transplant of a genetically modified pig heart into a human patient has been successful. The operation was performed by American surgeons and took place on Friday, January 7.

The patient in question is David Bennett, a citizen of Maryland. The 57-year-old was found to be ineligible for a human transplant. During the last months before his operation, he was kept alive by a machine. The day before his operation, he said it was his last choice.

Surgeons in full operation
Pixabay credits

The operation was approved by the Food and Drug Administration on New Years Eve.

A world first

According to Bartley Griffith, one of the surgeons who performed the transplant, it is a revolutionary operation that will bring us one step closer to solving the current organ shortage crisis.

Bennett’s donor pig had undergone a gene editing procedure to remove a gene responsible for producing a particular sugar. According to the explanations, this sugar could trigger a strong immune response and lead to rejection of the organ.

The biotechnology company Revivicor was responsible for the genetic modification. In October last year, the company also supplied a pig for a revolutionary kidney transplant in a brain-dead patient.

Before surgery, the heart was first stored in a machine. In addition to the usual anti-rejection drugs, the doctors also used a new drug made by Kiniksa Pharmaceuticals to suppress the immune system and thus prevent organ rejection.

The pig, an ideal donor for humans

Currently, approximately 110,000 people are awaiting organ transplants in the United States. Official figures indicate that more than 6,000 patients die each year before receiving a transplant.

To solve the problem of the shortage of donors, doctors have taken a great interest in xenotransplantation since the 17th century. It is an organ transplantation between different species.

Today, pigs are the most used donors, especially because of their rapid growth, size, large litters, as well as the fact that they are already raised as a source of food. Thus, in recent years, medicine has used pig skin as a graft on people who have suffered serious burns. There are also pig heart valves which are now widely used in humans.

SOURCE: Sciencealert

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6000 mAh, big screen and lots of storage for $175. Presented by Tecno Pova Neo

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The range of Tecno smartphones has been replenished with a new inexpensive model – Pova Neo. The novelty is presented in the markets of India and Nigeria, where it costs about the same – about $ 175. Early buyers in India are promised $20 wireless headphones as a bonus.

6000 mAh, big screen and lots of storage for $175.  Presented by Tecno Pova Neo

Tecno Pova Neo – from the category of “a lot of smartphone for little money.” It is equipped with a large 6.8-inch screen with a frame rate of 120 Hz, but the resolution is small – 1640 x 720 pixels. The main camera is represented by two sensors, the resolution of the main one is 13 megapixels. The front camera uses an 8MP sensor and an F/1.8 lens.

6000 mAh, big screen and lots of storage for $175.  Presented by Tecno Pova Neo

At the heart of the hardware platform is a MediaTek Helio G25 SoC paired with 6GB of LPDDR4X memory and 128GB of eMMC 5.1 memory. The device supports RAM expansion technology by creating a 5 GB virtual partition in flash memory. The device also includes an LTE modem, 802.11ac Wi-Fi and Bluetooth 5.1 adapters, a standard headphone jack, and a USB-C port. The battery capacity was 6000 mAh, it supports 18 W charging. The operating system is Android 11 with HiOS 7.6 interface.

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These are the most realistic artificial voices of the moment

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We are used to hearing computer generated voices on different devices. In smart assistants, in gadgets, in ebook readers, on websites…. these voices are more and more present, but they continue to feel artificial, something that will cease to be so in a few years.

The fact is that there are already artificial intelligence engines capable of creating voice systems that are extremely natural, and today I will show you where to listen to them.

Is about vocalora.com, a web project that uses one of the world’s most sophisticated speech engines to simulate the voice of 5 different English accents, using 18 different voices in the process.

We can paste a text (in English) and select the desired voice from all the available ones. Once done, we will click on the Read Text button that appears on the right. If during the reading process we put a different voice, both will be heard at the same time.

Both male and female voices and children’s voices are available, and the result is so impressive that it is difficult to understand how our vacuum cleaner continues to speak with an 80’s movie voice.

We can try vocalora for free, but if we need readings of several hours, we will have to go through the premium subscription (about 20 dollars per month).

At the moment there are no projects with the same quality in Spanish, at least not on a website of these characteristics, available to the general public, although it is a sector that is advancing a lot, so it will not be long before we have something like this soon in our language.

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Mobile GeForce RTX 3070 Ti is faster than Titan RTX and nearly as fast as Radeon RX 6800

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On January 5 at CES 2022, Nvidia introduced new graphics cards, including the mobile GeForce RTX 3080 Ti and GeForce RTX 3070 Ti. During the announcement, Nvidia revealed that the top model is faster than the desktop GeForce Titan RTX, but what about the GeForce RTX 3070 Ti? Now this 3D accelerator has been tested in Geekbench (as part of the MSI Vector GP66 laptop), and in the OpenCL test, it showed a result exactly on the level of Titan RTX. What’s more, the desktop Radeon RX 6800 isn’t far ahead.

Mobile GeForce RTX 3070 Ti is faster than Titan RTX and nearly as fast as Radeon RX 6800

Given that GeForce RTX 3070 Ti laptops start at $1,500, this is a very good deal for both gamers and those looking to purchase a laptop for professional use. Mobile PCs with the GeForce RTX 3080 Ti are already much more expensive, starting at $2,500. Interestingly, the Radeon RX 6800 retails for around the same $1,500, so users will have the choice of buying just the graphics card for the same amount, or an entire laptop with graphics performance nearly equivalent to that graphics card.

Mobile GeForce RTX 3070 Ti is faster than Titan RTX and nearly as fast as Radeon RX 6800

Mobile GeForce RTX 3070 Ti is faster than Titan RTX and nearly as fast as Radeon RX 6800

Recall that the mobile GeForce RTX 3070 Ti is built on a GA104 GPU with 5888 CUDA cores with a frequency of 1035-1485 MHz. The GPU is connected to 8GB of 14GHz GDDR6 memory via a 256-bit bus.

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