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Scientists succeed in implanting a model of the human brain Scientists succeed in implanting a model of the human brain

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Scientists succeed in implanting a model of the human brain into the head of a rat

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Scientists have transplanted a human brain organoid into newborn rats. An article about this was published in Nature.

Scientists succeed in implanting a model of the human brain into the head of a rat

Experiments on humans, including on their brains, can be difficult, can cause harm, and are severely restricted by law. In this regard, scientists are growing brain organoids – models that are a conglomerate of interconnected nerve cells. To test the work of the organoid, they tried to transplant them into animals, but did not succeed.

Sergiu Pasca of Stanford University and his colleagues were able to implant a brain organoid in a rat. They transferred the brain organoid to newborn rats, not to adult rats, as their colleagues did. During this period, the brain had not yet completed its development, which allowed the organoid to take root and integrate into its structure. In addition, the mice did not have a thymus, which means that their adaptive immunity could not attack the transplant.

The brain organelles not only took root in the brains of rats: the scientists noted a nine-fold increase in graft volume three months after the operation. Moreover, vessels and microglial cells, macrophages of the nervous system, appeared inside it.

The cells of the brain organoid, which was built into the body of rodents, began to differ from those grown in vitro. They are larger and express genes associated with the maturation of neurons, which means that scientists have achieved the development of an organoid in a living organism.

In addition, the implanted tissue was associated with the rats in an unexpected way. For example, organoid cells were activated when a rat’s whiskers were touched. The authors hope that their method of growing organelles will make it possible to fully investigate the work and development of the human brain.

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Components

GeForce GTX 1060 finally retires. GTX 1650 tops Steam stats, though it depends how you count it

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GeForce GTX 1060 finally retires GTX 1650 tops Steam stats

The Steam stats have been updated, and there are tangible changes again.

GeForce GTX 1060 finally retires.  GTX 1650 tops Steam stats, though it depends how you count it

The GeForce GTX 1650 knocked the GTX 1060 off its pedestal in one big leap to become the most popular 3D gaming card… if you just look at the table.

Recall that with the release of the RTX 30 line in Steam statistics, mobile and desktop cards of this generation began to be displayed separately, while before that they were all displayed together under one name. Thus, the GTX 1650 takes 6.27%, and the RTX 3060, if you add the mobile and desktop versions, takes 8.04%, so the RTX 3060 is the most popular video card among Steam gamers, and will probably remain so for more for a very long time.

GeForce GTX 1060 finally retires.  GTX 1650 tops Steam stats, though it depends how you count it

Returning to the castling in the table, the GTX 1060 has been in first place for the last couple of years, if not more, but this card has not been on sale for a long time, and the GTX 1650 is still available. In just one month, the newer card gained 0.66 percentage points while the GTX 1060 lost 1.85 percentage points for some reason. By the way, the RTX 2060 also sank very strongly (by 1.46 p.p.), and the share of the desktop RTX 3060 fell by 2.06 p.p., which is very strange.

In terms of processors, AMD’s share jumped 3.88 percentage points over the month to 32.87%. The most popular on Steam are six-core CPUs with a share of 33.52%, the share of processors with four cores is 30.07%, and eight-core processors occupy 19.19%.

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Gaming

“This is a true continuation of Dead Space”, “The best horror game of the year”, the horror movie The Callisto Protocol went on sale

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This is a true continuation of Dead Space The best

The Callisto Protocol, a sci-fi action horror game created by Striking Distance Studios, went on sale today.

  “This is a true continuation of Dead Space”, “The best horror game of the year”, the horror movie The Callisto Protocol went on sale

At the same time, reviews of Western publications appeared on the network, which were collected on the Metacritic aggregator. Over 60 reviews have already been published for all versions, including 37 articles for the PlayStation 5, which received 76 points out of 100 possible. The PC and Xbox versions received 75 points each.

In general, the game is praised for its atmosphere, modern graphics, high-quality animation, combat system with new dodge mechanics, but criticized for the lack of scary moments, low variety of enemies, clichéd story and technical problems on PC.

  “This is a true continuation of Dead Space”, “The best horror game of the year”, the horror movie The Callisto Protocol went on sale

Below are quotes from reviews of various publications:

The Callisto Protocol is the true sequel to Dead Space that we never had, and Glen Scofield had to return to the horror genre.

Jeux Actu (90/100)

The Callisto Protocol gave me nightmares. This is the best horror game of the year and a bright new contender in the survival horror genre.

Gfinity (90/100)

The Callisto Protocol, for all its tension, cannot hide the horrors within.

Wcftech (72/100)

Bloody and grim, The Callisto Protocol doesn’t go against the horror formula, but instead uses all of its beats and clichés to tell a dark sci-fi story laced with menace.

PC Gamer (79/100)

A fantastic looking game that builds a great sci-fi world only to destroy it with nasty combat missions.

GamesRadar+ (60/100)

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Components

128-core AMD processors to compete with Arm will be released in the first half of 2023

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128 core AMD processors to compete with Arm will be released

AMD previously introduced the Genoa Epyc server processors with 96 cores in the maximum configuration, and now told when to expect 128-core CPUs.

128-core AMD processors to compete with Arm will be released in the first half of 2023

These will be the Epycs of the Bergamo line, but they will receive slightly different cores than Genoa. The new CPUs will be based on Zen 4C cores, which will be somewhat simplified from regular Zen 4 cores for better power efficiency. According to AMD, Bergamo processors will also compete with server solutions based on the Arm architecture.

Bergamo will be released in the first half of 2023, will receive the same SP5 performance as Genoa. Later in the year, AMD will also release Sienna processors aimed at the telecommunications segment, but there are no details about them yet. However, as we can see, AMD is clearly placing a huge emphasis on the server market, which the company has already directly spoken about.

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