

News
Artificial intelligence to improve chemotherapy dosing
As is well known, chemotherapies are extremely aggressive treatments that are currently used as the most effective solution to try to eradicate cancer.
Given the strong physical impact of this treatment, interest arose in trying to mitigate its effects. Under this motivation, a team from the American Case Western Reserve University developed an AI system to offer a more precise dosage of this therapy.
Less invasive chemotherapy
In this case, they asked the computer to analyze digitized images of tissue samples that had been taken from 439 patients across six hospital systems with a type of head and neck cancer known as human papillomavirus-associated oropharyngeal squamous cell carcinoma. (HPV) (OPCSCC).
Although most others with HPV-driven cancer would still benefit from aggressive treatment, along with patients whose cancer was unrelated to the virus, the researchers said their study revealed that a significant group were receiving more aggressive HPV therapy. what they needed to achieve a favorable outcome.
Doctors can’t easily make that distinction simply by simply looking at tissue scans, the researchers said. Therefore, virtually all patients with these cancers, regardless of whether they are HPV-driven or not, are treated with a full course of chemotherapy and radiation.
“We’ve been overtreating a lot of patients with chemotherapy and radiation that they don’t need because we didn’t have a way to find out which patients would benefit from de-escalation.”said Anant Madabhushi, director of the CCIPD, professor at the Donnell Institute for Biomedical Engineering in the Case School of Engineering and responsible for this study. “We’re saying now we do, and one day doctors could modulate how we care for people and not just give the standard high dose of radiation to everyone who walks in the door.”.
Madabhushi said reducing radiation for these patients could also help decrease “radiotherapy toxicity,” meaning they might experience fewer side effects such as dry mouth, swallowing dysfunction and changes in taste.
“There are already ongoing national clinical trials investigating reducing the intensity of radiotherapy and chemotherapy in patients with HPV-positive oropharyngeal cancer”said Shlomo Koyfman, director of head and neck and skin cancer radiation at the Cleveland Clinic and a collaborator on the study. “However, properly selecting ideal patients for this treatment reduction has been challenging. This image classifier can help us better select patients for these new treatment paradigms”.
The computer program successfully identified a subset of patients who might have benefited from a significantly reduced dose of radiotherapy.
While that analysis was retrospective, meaning the computer analyzed data from patients where the end result was already known, the researchers said their next step could be to test its accuracy in clinical trials.
His research was recently published in the Journal of the National Cancer Institute.
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Phones
Is this iPhone possessed by the devil? The girl took a picture of herself in front of the mirrors and discovered that the reflections in the mirrors did not match her pose.

Modern mobile photography is increasingly turning into computational photography every year. And sometimes this results in very interesting incidents, as in the photo below.
At first glance, it may seem that everything is in order with the picture. But if you look more closely, you can see that the girl who published this photo looks different in two neighboring mirrors, and besides, neither of the mirrors reflects the girl’s real pose.
Creating such an image in Photoshop or another editor is not difficult, but the caveat is that this photo was taken on an iPhone without any further processing.
The reason for this result is actually quite simple. For some reason, the iPhone algorithms mistook the girl’s reflections for other people, and since modern photos are taken by gluing together many instantly taken photographs, we see that from somewhere in this set of photos the iPhone took one girl, from somewhere else, and then I glued it all together.
The funny thing is that in the past, when there was no talk of any modern smartphones or cameras, such a photo could have been regarded as the work of the devil.
News
Xiaomi has finally announced pre-sales of the titanium Xiaomi 14 Pro

Despite the fact that the official premiere of the Xiaomi 14 Pro Titanium Special Edition with a titanium case took place on October 26, it has not yet reached real sales. But some progress has already been made: the company has announced a date for pre-orders in China.
They will begin to be accepted on the Xiaomi Mall branded marketplace and other large platforms from December 5. It has not yet been announced when open retail sales will start. And it’s unlikely that things will come to this soon: on the Weibo social network, a Xiaomi representative said that the device will be available “in small quantities.”
Let us remind you that in terms of characteristics, the Xiaomi 14 Pro Titanium Special Edition is no different from the regular Xiaomi 14 Pro, the availability of which has no problems. But it has a titanium frame (99% titanium alloy) and only one configuration with 16 GB of RAM and 1 TB of flash memory. They are asking $920 for the titanium flagship.
News
Without 200 megapixels, but with flicker-free screens, new platforms and improved cameras. Honor 100 and Honor 100 Pro go on sale in China

Today, official sales of the Honor 100 and Honor 100 Pro smartphones started in China (their official premiere, we recall, took place a week ago).
The older model is offered in four configurations: 12/256 GB – $475, 16/256 GB – $525, 16/512 GB – $550, 16 GB/1 TB – $625.
The cost of the younger one is as follows: 12/256 GB – $350, 16/256 GB – $400, 16/512 GB – $450.
Honor 100 is built on the Snapdragon 7 Gen 3 SoC, equipped with a 6.7-inch OLED screen with a resolution of 1.5K and a frame rate of 120 Hz. The Honor 100 Pro SoC Snapdragon 8 Gen 2 and an OLED screen with a diagonal of 6.78 inches, a resolution of 1.5K and a frame rate of 120 Hz. The PWM control frequency of both models is 3840 Hz, so the displays do not flicker. The smartphones also received 5000 mAh batteries with support for 100-watt wired charging (the Pro version also supports wireless charging).
The Honor 100 Pro no longer has a 200-megapixel sensor in the main camera, but it has been replaced with a 50-megapixel Sony IMX906 of the top line. The camera of this model also has a 12-megapixel sensor (in the module with an ultra-wide-angle lens) and a 32-megapixel sensor (in the module with a telephoto lens). The younger model does not have a module with a 32-megapixel sensor.
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